Product Name: Jervine
Description: Jervine is an inhibitor of Hedgehog signaling (IC50 = 500 – 700 nM), which binds directly to Smoothened (Smo), and inhibits the response of target tissues to Sonic hedgehog signaling, possibly via the sterol sensing domain of Patched.
Formula: C27H39NO3
M.WT: 425.6
CAS NO: 91757-46-9 Product: NSC 601980 (analog)
Purity: >98 %
Solubility: Soluble to 50 mM in ethanol and to 20 mM in DMSO
Chemical Name: (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2
Synonyms: N/A
Storage: Store at -20°C
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