Biotinylated Human SIRP alpha V3 Protein 3509

Additional Information:
express systemHEK293|product tagC-His-Avi|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundSignal regulatory protein (SIRP) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRP acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the “dont eat me” signal.Cancer cells highly expressed CD47 that activate SIRP and inhibit macrophage-mediated destruction.|molecular weightThe protein has a predicted MW of 39.8 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Biotinylated Human SIRP alpha V3 Protein 3509proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceNo information|