The pursuit of intelligent, durable, and biocompatible materials for wearable electronics demands a harmonious integration of mechanical robustness, electrical conductivity, and self-repair capability. In this work, we report the design and realization of a supramolecular double-network conductive hydrogel (PAAN) that achieves an unprecedented balance among these three critical properties. By pre-infiltrating a polyaniline (PANI) precursor into a self-healable hydrophobic association poly(acrylic acid) (HAPAA) matrix followed by in situ polymerization, we construct a hybrid network where dynamic interfacial interactions—hydrogen bonding and electrostatic forces—mediate between the rigid PANI chains and the flexible HAPAA matrix. These interactions serve as reversible sacrificial bonds that dissipate energy during deformation, enabling the PAAN hydrogel to exhibit outstanding mechanical performance: tensile strength of 0.9 MPa, elongation at break up to 2590%, toughness of 7.85 MJ m⁻³, and fracture energy exceeding 4200 J m⁻²—surpassing most synthetic gels and approaching natural tissues like skin and cartilage. Remarkably, this enhanced mechanical integrity does not compromise self-healing; instead, the abundance of dynamic bonds at the cut interface ensures rapid and efficient recovery. After 24 hours of healing, the hydrogel regains over 92% of its original electrical conductivity without external stimuli, demonstrating fully recoverable electronic function. The interconnected PANI network provides high electrical conductivity (~3.35 S m⁻¹) and exceptional sensing performance, including a gauge factor of 17.9, a detection limit of just 0.05% strain, and a response time of 80 ms. The material also exhibits excellent electrical stability, maintaining consistent signal output over 2500 stretching cycles with less than 6% resistance drift. We demonstrate its practical utility in multiple wearable applications: real-time monitoring of human joint motion, physiological signals such as pulse and speech, flexible touch screens for handwriting recognition, and artificial electronic skin capable of mapping pressure distribution across surfaces.315-22-0 Biological Activity The low modulus (~52 kPa) ensures minimal mechanical mismatch with soft biological tissues, enhancing comfort and long-term usability.154598-52-4 IUPAC Name This study presents a rational design strategy based on dynamic interfacial engineering that resolves the fundamental trade-offs in hydrogel performance, offering a scalable and versatile platform for next-generation wearable sensors, soft robotics, and intelligent human-machine interfaces.PMID:25905203 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
