This study investigated the association between serum polyunsaturated fatty acid (PUFA) levels and homocysteine concentrations among a cohort of Japanese men and women with high habitual intake of n-3 PUFAs.…
**Background** Type II diabetes is a chronic metabolic disorder characterized by insulin resistance and elevated blood glucose levels, which can lead to severe systemic complications. The orphan nuclear receptor Nur77…
Scientific conferences play a vital role in advancing knowledge, fostering collaboration, and disseminating research across disciplines. However, the environmental cost of attending these events—particularly through air travel—has increasingly come under…
The human intestinal tract hosts a vast and diverse microbial community, with up to 10¹¹ bacteria per milliliter in the colon. This microbiota plays a crucial role in digestion, metabolism,…
**Background** The WNT signaling pathway plays a critical role in regulating cell proliferation, differentiation, and stem cell maintenance. Aberrant activation of this pathway is frequently associated with the progression of…
Preeclampsia is a serious pregnancy-related disorder affecting 5% to 8% of pregnancies, posing significant risks to both mother and fetus. Despite extensive research, its pathogenesis remains incompletely understood. Recent studies…
**Background** Rheumatoid arthritis and other autoimmune diseases are characterized by the uncontrolled proliferation of activated lymphocytes, leading to chronic inflammation and tissue destruction. A key requirement for the expansion of…
Fetal DNA is present in the plasma of pregnant women, offering a unique opportunity for noninvasive prenatal testing. Massively parallel sequencing (MPS) of maternal plasma DNA has already been successfully…
**Background** The innate immune system of plants and algae relies on the recognition of pathogen-associated molecular patterns (PAMPs) to trigger defense responses. Among these patterns, flagellin, the primary protein component…
Genetic deficiency of cholesteryl ester transfer protein (CETP) leads to markedly elevated plasma levels of high-density lipoprotein cholesterol (HDL-C), characterized by an accumulation of large, buoyant HDL particles enriched in…