teraction between a higher factor VIII as well as the use of birth tablets control will result in an excess of thrombotic events. Conclusions: With regards towards the possible joint danger of VTE in patients with inherited or acquired thrombophilia below OCP, we recommend that physicians ought to recognize patients at a higher risk of thrombophilia and tailor the laboratory testing, ahead of starting on OCP.P R EG N A N C Y A N D P R EG N A N C Y C O M P L I C AT I O N SLPB0045|Principles of Care for Women and Girls with Inherited Bleeding Disorders K. van Galen1; M. Lavin2; N. Skouw-Rasmussen3; D. Noone3; D. Pollard4; K. Khair5; K. Gomez6; K. Fischer1; E. van Loon7; C. Bagot8; P. Elfvinge9; R. D’Oiron10; R. KadirVan Creveldkliniek, University Healthcare Center Utrecht, Utrecht University,Utrecht, Netherlands; 2Irish Centre for Vascular Biology, School of Pharmacy and Biomedical Sciences, RCSI, Dublin, Ireland; 3European Haemophilia Consortium, Brussels, Belgium; 4Dormandy Haemophilia Thrombosis Centre, Royal Cost-free London NHS Foundation Trust, London, Uk;Heamnet Foundation, London, United kingdom; 6Haemophilia Centreand Thrombosis Unit Haematologist, Royal Totally free London, London, United kingdom; 7UZ Leuven, Leuven, Belgium; 8Glasgow Royal Infirmary, Glasgow, Uk; 9Karolinska University, Stockholm, Netherlands; 10APHP Paris Saclay, H ital Bic re, Inserm U 1176, Le Kremlin Bic re, Paris, France; 11Royal No cost Foundation Hospital and Institute for Women’s Overall health, University College London, London, United kingdom Background: Regardless of increasing awareness from the troubles faced by girls and girls with inherited bleeding problems (WGBD) standards of care are lacking, with disparities in access to diagnosis and treatment for WGBD across the world. Aims: To define generalizable principles of care (PoC) in an iterative process, involving relevant stakeholders, with the eventual target to optimize diagnosis and management for WGBD. Solutions: Supported by the European Association for Haemophilia and Allied Disorders and following four IP Inhibitor Source multidisciplinary meetings of overall health care providers (HCPs) seasoned in WGBD care and European Haemophilia Consortium representatives, combined with broad patient and HCP consultations in the European haemophilia community, practical PoC have been formulated to promote standardization of care for WGBD inside Haemophilia Treatment/Comprehensive Care Centres (HTCs). Final results: Ten PoC for WGBD had been developed (Table 1) which strain the significance and benefits of a centralized, multidisciplinary, comprehensive, family-centred approach to assistance and manage WGBD at all life stages. These principles emphasise the right to CXCR7 Activator manufacturer Equitable access and high-quality of care for all people today with bleeding problems, irrespective of gender. TABLE 1 ten Principles of Care for Girls and Girls with inherited bleeding disorders1 2 three 4 Equitable access and excellent of care for all individuals with bleeding problems, irrespective of gender Timely and accurate diagnosis of bleeding disorders in girls and girls Awareness in the extra challenges faced by WGBD all through life Provision of complete care inside a loved ones centred approachABSTRACT951 of|five six 7 8 9Inclusion of a dedicated obstetrician and gynaecologist within the multidisciplinary group Education of WGBD and their households concerning the menstrual cycle and management Early recognition and optimal management of heavy menstrual bleeding Provision of pre-conception counselling and access to prenatal diagnostics Provi
