Product Name :
Geldanamycin, 98+%
Synonym:
IUPAC Name :
13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
CAS NO.:
30562-34-6
Molecular Weight :
Molecular formula:
C29H40N2O9
Smiles:
COC1CC(C)CC2=C(OC)C(=O)C=C(NC(=O)C(C)=CC=CC(OC)C(OC(N)=O)C(C)=CC(C)C1O)C2=O
Description:
Geldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90).Cefditoren (Pivoxil) HSP90 maintains the stability and functional shape of many oncogenic signaling proteins.Ficlatuzumab It interferes with conformational maturation of proteins and the cellular stress response.PMID:32695810 In addition, it is a potent inhibitor of the nuclear hormone receptor family.
