Product Name :
PD-1-IN-22
Description:
PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM.
CAS:
2349372-98-9
Molecular Weight:
459.50
Formula:
C25H25N5O4
Chemical Name:
N-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]-6-{[(2-hydroxyethyl)amino]methyl}-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide
Smiles :
CC1=C(C=CC=C1C1C=CC2OCCOC=2C=1)NC(=O)C1=CC(CNCCO)=CN2C=NN=C21
InChiKey:
IWOBHQNCHHSQSY-UHFFFAOYSA-N
InChi :
InChI=1S/C25H25N5O4/c1-16-19(18-5-6-22-23(12-18)34-10-9-33-22)3-2-4-21(16)28-25(32)20-11-17(13-26-7-8-31)14-30-15-27-29-24(20)30/h2-6,11-12,14-15,26,31H,7-10,13H2,1H3,(H,28,32)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Eltrombopag} medchemexpress|{Eltrombopag} Thrombopoietin Receptor|{Eltrombopag} Technical Information|{Eltrombopag} References|{Eltrombopag} custom synthesis|{Eltrombopag} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Metformin} medchemexpress|{Metformin} Autophagy|{Metformin} Technical Information|{Metformin} Purity|{Metformin} custom synthesis|{Metformin} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23074147
Additional information:
PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM.|Product information|CAS Number: 2349372-98-9|Molecular Weight: 459.50|Formula: C25H25N5O4|Chemical Name: N-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]-6-{[(2-hydroxyethyl)amino]methyl}-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide|Smiles: CC1=C(C=CC=C1C1C=CC2OCCOC=2C=1)NC(=O)C1=CC(CNCCO)=CN2C=NN=C21|InChiKey: IWOBHQNCHHSQSY-UHFFFAOYSA-N|InChi: InChI=1S/C25H25N5O4/c1-16-19(18-5-6-22-23(12-18)34-10-9-33-22)3-2-4-21(16)28-25(32)20-11-17(13-26-7-8-31)14-30-15-27-29-24(20)30/h2-6,11-12,14-15,26,31H,7-10,13H2,1H3,(H,28,32)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PD-1-IN-22 dose-dependently elevates IFN-γ secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells.|Products are for research use only. Not for human use.|
