Human CD160/BY55 Protein, ECD (Extracellular Domain), Fc-fusion, Biotinylated, Recombinant

Name :
Human CD160/BY55 Protein, ECD (Extracellular Domain), Fc-fusion, Biotinylated, Recombinant

Description :

Gene Symbol :
CD160; NK1; BY55; NK28

NCBI Gene ID :
11126

Uniprot Entry :
O95971

Construct Details :
The recombinant human CD160-Fc fusion is expressed as a 359 amino acid protein consisting of Ile27 – Thr157 region of CD160 and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions

Source :
Human cells stably expressing human CD160-Fc and growing in chemical-defined media with no animal components or antibiotics

Amino Acid Sequence: :
10 20 30 40 50 60 INITSSASQE GTRLNLICTV WHKKEEAEGF VVFLCKDRSG DCSPETSLKQ LRLKRDPGID 70 80 90 100 110 120 GVGEISSQLM FTISQVTPLH SGTYQCCARS QKSGIRLQGH FFSILFTETG NYTVTGLKQR 130 140 150 160 170 180 QHLEFSHNEG TSTGTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH 190 200 210 220 230 240 EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL 250 260 270 280 290 300 PAPIEKTISK AKGQPREPQV YTLPPSREEM TKNQVSLTCL VKGFYPSDIA VEWESNGQPE 310 320 330 340 350 NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK

M.W. :
Calculated molecular mass (kDa): 40.2 Estimated by SDS-PAGE under reducing condition (kDa): 45-50

Calculated PI :
7.67

Calculated Extinction Coefficients :
(M-1 cm-1, at 280nm): 44515

Endotoxin Level :
>95% judged by SDS-PAGE under reducing condition (see the gel image above, labeled as “DTT: +”)

Formulation :
Supplied at 0.5 mg/ml in sterile PBSpH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule) using the standard procedure.

Endotoxin Level :
<0.1 EU per 1 μg of purified recombinant protein determined by the LAL method

Biological Activity :
Binds to human HVEM protein (SKU#FCL0096) in a functional ELISA.

Molecule Class :
GPI-Anchored Protein

Gene Synonym :
<0.1 EU per 1 μg of purified recombinant protein determined by the LAL method

Gene Family :
CD160; NK1; BY55; NK28

Research Area :
Immunology

Pathway/Disease :
T Cell Costimulation

Species :
Human

CD Antigen :
CD160

References :

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: cot- tpi2

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