Name :
Human CD160/BY55 Protein, ECD (Extracellular Domain), Fc-fusion, Biotinylated, Recombinant
Description :
Gene Symbol :
CD160; NK1; BY55; NK28
NCBI Gene ID :
11126
Uniprot Entry :
O95971
Construct Details :
The recombinant human CD160-Fc fusion is expressed as a 359 amino acid protein consisting of Ile27 – Thr157 region of CD160 and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions
Source :
Human cells stably expressing human CD160-Fc and growing in chemical-defined media with no animal components or antibiotics
Amino Acid Sequence: :
10 20 30 40 50 60 INITSSASQE GTRLNLICTV WHKKEEAEGF VVFLCKDRSG DCSPETSLKQ LRLKRDPGID 70 80 90 100 110 120 GVGEISSQLM FTISQVTPLH SGTYQCCARS QKSGIRLQGH FFSILFTETG NYTVTGLKQR 130 140 150 160 170 180 QHLEFSHNEG TSTGTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH 190 200 210 220 230 240 EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL 250 260 270 280 290 300 PAPIEKTISK AKGQPREPQV YTLPPSREEM TKNQVSLTCL VKGFYPSDIA VEWESNGQPE 310 320 330 340 350 NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK
M.W. :
Calculated molecular mass (kDa): 40.2 Estimated by SDS-PAGE under reducing condition (kDa): 45-50
Calculated PI :
7.67
Calculated Extinction Coefficients :
(M-1 cm-1, at 280nm): 44515
Endotoxin Level :
>95% judged by SDS-PAGE under reducing condition (see the gel image above, labeled as “DTT: +”)
Formulation :
Supplied at 0.5 mg/ml in sterile PBSpH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule) using the standard procedure.
Endotoxin Level :
<0.1 EU per 1 μg of purified recombinant protein determined by the LAL method
Biological Activity :
Binds to human HVEM protein (SKU#FCL0096) in a functional ELISA.
Molecule Class :
GPI-Anchored Protein
Gene Synonym :
<0.1 EU per 1 μg of purified recombinant protein determined by the LAL method
Gene Family :
CD160; NK1; BY55; NK28
Research Area :
Immunology
Pathway/Disease :
T Cell Costimulation
Species :
Human
CD Antigen :
CD160
References :
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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