Product Name: SGC 0946
Description: SGC 0946 is a potent DOT1L methyltransferase inhibitor (KD = 0.06 nM, IC50 = 0.3 nM in a radioactive assay) which blocks H3K79 methylation in A431 cells and MCF10A cells (IC50 values are 2.65 and 8.8 nM respectively).
Formula: C28H40BrN7O4
M.WT: 618.57
CAS NO: 140926-75-6 Product: NSC5844
Purity: >99 %
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Chemical Name: 1-[3-[[[(2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl](isopropyl)amino]propyl]-3-[4-(2,2-dimethylethyl)phenyl]urea
Synonyms: N/A
Storage: Store at -20°C
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