Product Name: HKI 357
Description: HKI 357 is a potent, irreversible inhibitor of ErbB2 (HER2) and EGFR that suppresses ligand-induced EGFR autophosphorylation and cell proliferation in NCI-H1975 cells containing L858R and T790M mutations.
Formula: C31H29ClFN5O3
M.WT: 574.05
CAS NO: 156223-05-1 Product: GTS-21 (dihydrochloride)
Purity: >98 %
Solubility: Soluble to 100 mM in DMSO and to 25 mM in ethanol
Chemical Name: (2E)-N-[[4-[[(3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Synonyms: N/A
Storage: Store at -20°C
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